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In addition to these core areas, many surgeons include other zones in a 12-area plan, such as the arms, neck, chin, and legs , covering both inner and outer thighs, knees, and calves

La particularidad de la sinefrina es que acta sobre los receptores adrenrgicos beta 3, que son los responsables directos de activar la liplisis y la movilizacin de las grasas, pero sin afectar la presin sangunea o la salud cardiovascular y lo hace activando las hormonas catecolaminas, como la epinefrina y la norepinefrina