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Both medications have potential long-term risks, such as hormonal imbalances with Sermorelin and gastrointestinal or cardiovascular issues with Semaglutide

[17] found that blocking GH receptors with pegvisomant selectively suppressed lipid mobilization and oxidation after 36 h fast

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In November 2024, CMS proposed a rule change that would have allowed Medicare Part D to cover drugs prescribed for weight loss to treat obesity, starting in 2026