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The platelet glycoprotein Ib-von Willebrand factor interaction activates the collagen receptor alpha2beta1 to bind collagen: activation-dependent conformational change of the alpha2-I domain

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Liver-derived acylcarnitine can be used as a signal molecule for inter-tissue communication to coordinate energy metabolism, highlighting the role of the liver as a metabolic center, and unveiling the new insight of the liver-organ axis

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At week 68, treatments (including lifestyle intervention) were discontinued and an offtreatment extension followed a representative subset of participants for a further year