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A follow-up study over 11 months revealed that individuals whose BMI decreased by 15% or more during treatment had a 37% lower risk of osteoarthritis, a 30% lower risk of chronic kidney disease, a 69% lower risk of obstructive sleep apnea syndrome , and a 32% lower risk of heart failure compared to subjects whose BMI decreased by 0-5% during the treatment period

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A 2015 review documented activity across skin, lung, bone, liver, and GI tissue models

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Between January and March 2025, all participants aged 18 years in England and ~ 50% in Wales and Scotland were asked additional questions on past-year use of GLP-1 and GLP-1/GIP medications and interest in using them for weight loss