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74 Preparation of samples for metabolomics analysis For quantitative metabolite profiling, SHP2-expressing cells were treated with 15 M SHP099, 10 nM trametinib, or their combination for 12, 48, or 72 h

doi: 10.1177/1060028019899152 123 EdinoffANSandersNMLewisKBApgarTLCornettEMKayeAMet al

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