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One of the most frequently observed mtDNA mutations is the large-scale 4977-bp deletion, also known as the common deletion, which spans several OXPHOS genes and is often flanked by direct repeats that predispose these regions to slipped-strand mispairing during replication [21, 22]

In the CAE model, pharmacological inhibition of citrullination is a potent suppressor of inflammatory demyelination after an immune stimulation, in the absence of any direct anti-inflammatory effect by the inhibitors themselves, indicating that proteins modified in this manner can be potent antigenic targets (Caprariello et al., 2018)

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This matters tremendously because disinhibited eating often reflects emotional eating, stress eating, or binge eating

Detergent-free incorporation of a seven-transmembrane receptor protein into nanosized bilayer lipodisq particles for functional and biophysical studies