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A surrogate result is weaker evidence than an outcome result

12 , e2202959 (2023)

& Juhasz, C

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

Menopause also increases the risk of insulin resistance , which can cause blood sugar levels to rise