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Previous analyses have suggested a larger benefit of SGLT-2 inhibitors, as compared with GLP-1RA, on cardiorenal events

however, it has been seen that the prevalence of NAFLD in patients with T2DM was 56.8 % [7,8] and T2DM was present in 85 % of the patients diagnosed with NAFLD [9], associated with the fact that most of these patients meet the criteria for the definition of metabolic syndrome, which is the mainstay of the diagnosis of MASLD

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The German BfArM and equivalent agencies (ANSM in France, AEMPS in Spain, AIFA in Italy, URPL in Poland) treat unauthorized human use of these compounds as outside the scope of the marketing authorization regime entirely

Cyanocobalamin includes a trace cyanide component, but its clinically insignificant in therapeutic doses and quickly cleared