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The medication influences cardiovascular function through multiple mechanisms: it slows gastric emptying, reduces appetite, improves glycaemic control, and may have direct effects on the cardiovascular system including modest reductions in blood pressure and a slight increase in heart rate

Energy returns

Several factors affect GLP-1 secretion, including: Diet: High-fiber foods and healthy fats can enhance GLP-1 release

Blood pressure and heart rate monitoring provide adequate safeguards, particularly for sympathomimetic agents like phentermine that serve as viable alternatives for GLP-1 non-responders

For women using GLP-1 receptor agonists, whose therapeutic benefit depends significantly on recalibrating appetite regulation, chronic sleep disruption can work directly against the therapy's mechanism