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Although the use of DPP-4 inhibitors is associated with increased bone formation, their effects are more associated with mechanisms related to the suppression of bone resorption

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They need to be prescribed appropriately, with tailored wraparound support alongside them, to ensure people can fully benefit and maintain weight loss for as long as possible when they stop taking the medication. Katharine Jenner, the executive director of the Obesity Health Alliance, said regaining weight after stopping treatment was not a failure of individuals, but rather reflects the reality of living in a food environment that continually pushes people towards unhealthy options. These drugs can create a window of opportunity to improve the food environment at scale and pace from junk food marketing to the affordability and availability of healthier food otherwise many people will struggle to sustain the health benefits of weight loss drugs over the long term, Jenner said

Long-term data in adolescents is still emerging

Even if youre taking a GLP-1 medication, that may not be the only reason or even the main reason youre experiencing diarrhea