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For treatment of primary systemic carnitine deficiency, a genetic impairment of normal biosynthesis or utilization of levocarnitine from dietary sources, or for the treatment of secondary carnitine deficiency resulting from an inborn error of metabolism such as glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency

[25] This appraisal is useful context for understanding how similar agents are evaluated in the UK, but it does not apply directly to retatrutide, which remains unlicensed

AsghariHanjani N, Vafa M

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Shiomi, Delta-sleep-inducing peptide (DSIP) stimulates the release of immunoreactive Met-enkephalin from rat lower brainstem slices in vitro, Elsevier BV, Feb