To generate a site-specific antibody to detect the R76-methylated GLUD1 [meGLUD1(R76)], synthesized R76me1 peptide (GL Biochem (Shanghai) Ltd.) was coupled to KLH as an antigen to immunize two rabbits
The research-use-only framework supports scientific integrity by ensuring compounds like 5 Amino 1MQ are used within the right experimental context
Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials
Crit Care 23:196
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