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Enrollment, follow-up, data analysis, NDA (New Drug Application) preparation, and FDA review typically add up to 18-36 months even with Breakthrough Therapy Designation, which Lilly has received for retatrutide in obesity

Timing adjustments alone will not prevent GLP-1 related hair loss , which is typically caused by rapid weight loss and nutritional deficiencies rather than the timing of the injection itself

A nutritious and balanced diet, low in processed foods and sugars, and high in whole grains, fruits, and vegetables, can help promote health and facilitate weight loss

It is also not recommended for use in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, as semaglutide may increase the risk of these conditions

Obesity then became the breakthrough market