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The pro-inflammatory cells and cytokines also interact with obesity, steroid hormones imbalance and IR, leading to increased metabolic imbalance and reproductive-endocrine dysfunction in PCOS patients

a , 3D PCA plot with genes plotted in three dimensions using their projections onto the first three principal components, and nine samples plotted using their weights for the components ( n = 3 independent experiments)

Patra D, Roy S, Arora L, Kabeer SW, Singh S, Dey U, et al

How It Is Studied In laboratory research, AOD-9604 is typically administered to cell cultures or animal models and assessed using lipolysis assays, which measure free fatty acid release from adipocytes

However, due to limited human clinical trials, long-term safety is not fully understood