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Its mechanisms of action are primarily related to anti-inflammatory, anti-oxidative stress, pro-apoptotic and anti-apoptotic effects, anti-fibrosis, autophagy regulation, anti-ERS, and metabolic regulation
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Multiple studies have demonstrated that testosterone administration, whether injectable, transdermal, or implanted, reliably suppresses spermatogenesis
Low toxicity, resistances to hydrolysis and low protein adsorption make suitable for drug delivery system such as hydrogels, micelles, nanoparticles and also polymer drug conjugates for various applications including tissue engineering and biofouling resistance coating for medical devices [73,74,75]
Omenn GS, Goodman GE, Thornquist MD, et al
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