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At the end of the study, 33% of the Pycnogenol subjects reported the complete disappearance of leg heaviness and 63% did not feel any swelling
The genotoxicity of FA can be prevented by ICL-DNA repair factors, and indeed FA can lead to bone marrow failure and cancer when those DNA repair mechanisms fail 9
The temporary nature of effects also reinforces that glutathione is supporting natural processes rather than fundamentally changing your skin's biology
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