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1 Introduction The world population has increased by 14% in the past 12 years, reaching the 8.0-billion milestone in 2022, and is expected to continue, peaking at 9.7 billion in 2050 and 10.9 billion in 2100 (United Nations Department of Economic and Social Affairs, 2021)

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Under conditions of intermittent fasting (IF), caloric restriction (CR), KD and exercise, FFA undergoes extensive -oxidation in the liver, yielding a significant quantity of ACAC

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A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions