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Inhibition of the PI3K/AKT also leads to decrease in TNF-, IL-6, MMP-2, and MMP-9 production, which suppresses cell proliferation and invasion, and promote apoptosis in cultured RA-FLS 54

Eknoyan G, Latos DL, Lindberg J

10.1046/j.1528-1157.2001.18001.x Epilepsia

We have developed a diverse, robust, and reproducible monoallelic HLA-DRB1 system in professional antigen presenting cells capable of examining the immunogenic potential of any human IgG

doi: 10.1007/164_2019_337