is depression a side effect of tirzepatide Does Make You Angry? Mood Effects Explained Can Tirzepatide Cause Depression? A

doi:10.1159/000507370 8

The third mechanism involves the presence of GLP-1 receptors in the sinoatrial node [46, 47], and it is proposed that GLP-1 receptor agonists may directly act on the sinoatrial node to induce tachycardia [48]

For people with severe obesity (body mass index 35 kg/m 2 ) and T2DM, evidence from bariatric surgery suggests that the earlier after the T2DM diagnosis that significant WL is achieved and maintained, the lower is the long-term risk for developing micro- and macrovascular complications

Triple agonists like retatrutide are emerging as next-generation options with potentially different side effect profiles

The STEP UP trial ran 72 weeks with a 9 week follow up, according to the public record