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In this context, incretin hormonesparticularly GIP and GLP-1are recognized as central regulators of glucose metabolism and have become important therapeutic targets

Research Use Only no claims are made regarding any use or effectiveness in humans.

Medicare explicitly excludes coverage for weight-loss medications (unless there are associated cardiovascular risks)

Statistical differences between stimulants were calculated with Students t -test

Yet beneath the extraordinary clinical results and the unprecedented commercial momentum lies a fundamental contradiction that the industry has largely avoided confronting: despite the breadth of physiological systems these agents appear to influence, we still lack a unified and reproducible mechanistic model capable of explaining their full biological scope