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Caleosins can react directly with -linolenic acid to introduce an epoxide group at any of the double bonds, and they can react with the 13lipoxygenase metabolite to produce a 13-hydroxy,15,16-epoxy-octadecadienoic acid

E., Wasdell, M

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Cabu et al

also showed the same trend in knee symptoms and daily activity progression using the mean KOOS score in ten participants with degenerative meniscus tears without osteoarthritis according to Stoller classification after 3 months and 6 months of follow up (i.e., KOOS: 56.6 15.7 baseline, 70.2 16.8 post- 3 months, 72.7 18.5 post- 6 months, p = 0.0007)