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In fact, increased activation of mTORC1 has a positive correlation with the overproduction of autoantibodies and cytokines in the B cells in SLE (64, 65)

The activation of UPR mt has been widely recognized as a common feature linking longevity pathways in long-lived mutants of C

Resveratrol Sirtuin 1(Sirt1), an NAD-dependent deacetylase, inhibits apoptosis in mammalian cells

FGF19 can synergize with Wnt signaling to accelerate mitogenic activity, thereby enhancing regeneration in vivo