In such an abundance of glucose, insulin also stimulates the synthesis of glycogen by phosphorylation of glycogen synthase kinase 3 (GSK3), which leads to dephosphorylation and activation of glycogen synthase (McManus et al., 2005)
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Biochimica Biophysica Acta 1863 (10), 24222435
Increasing GLP-1 production without managing the DPP-4 enzyme means the additional hormone gets rapidly broken down before it can exert full effects
The medical conversations overlap too