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In essence, while nanoencapsulation holds nutritional promise, a parallel effort is needed to rigorously evaluate and ensure the health safety of these novel delivery systems
Interestingly, inhibition of NLRP3 inflammasome activation reversed the M1 polarization of TMAO-stimulated macrophages, suggesting that NLRP3 plays a crucial role as a proteolytic activator in TMAO-induced macrophage responses
Biomedicines 12 (10), 2338
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