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Weight gain often becomes more noticeable during this time, particularly as fat distribution shifts more toward the abdomen, even if overall weight doesnt drastically change. But maintaining a healthy weight during menopause isnt just for your physical appearance

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Nonetheless, the present data support mimicry of the physiological function of circulating adiponectin by metformin, which controls incretin-mediated hypoglycemic episodes

For instance, mechanical perturbations of lipid rafts activate the enzyme phospholipase D2 to produce phosphatidic acid, which acts as a signaling lipid (Petersen et al., 2016)

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