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Together, these findings suggest that systemic GLP-1R agonists suppress food intake via aversive and non-aversive pathways in the pons via GLP-1R-expressing LC and LDTg neurons, respectively

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Why this happens is not fully clear yet, but researchers are guessing that by keeping food in the stomach for longer, Incretin Mimetics reduce appetite and keep you feeling full for longer, reducing how much you eat