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In 2023, these states spent the most on GLP-1 weight loss drugs (in millions), in descending order: Texas with $6 billion
Some patients use semaglutide for defined periods to achieve target weights, then taper or discontinue
Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure
Initial Management and Education Starting Dose: Semaglutide 0.25 mg once weekly (to minimize gastrointestinal side effects), with a plan to titrate to 1.0 mg weekly over several weeks
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