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3.3.2 TIM-3 as a potential target TIM-3 is another checkpoint that negatively regulates T cell responses

doi: 10.1089/thy.2016.0256 265

Regulating Cell Death Apoptosis Apoptosis is a type of programmed cell death characterized by cell atrophy, apoptotic body formation, and chromatin condensation

Furthermore, the potential for this therapeutically desirable property was not suggested from the measurement of acute cAMP responses in CHO-GLP-1R cells, a standard in vitro metric for GLP-1R agonist performance in drug development 23 , where the more insulinotropic compounds displayed reduced potency vs