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Many wellness programs combine them because glutathione supports liver health and reduces oxidative stress, which may help manage the metabolic changes and minor side effects associated with semaglutide

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However, when combinedespecially in large amountsthey can interfere with each others metabolism and increase the risk of liver injury

Cui M, Aras R, Christian WV, Rappold PM, Hatwar M, Panza J, et al

The term "master antioxidant" is widely used to describe glutathione it is an educational descriptor reflecting its dual role, not a regulatory or medical classification