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This means many patients face a choice between indefinite medication use with its ongoing financial costs and health considerations, or accepting that some or most weight may return after discontinuation

The exact rates vary by study and population, but think roughly 1-4% in some obesity studies, closer to 1% or less in diabetes studies

the other restores the entire growth hormone cascade that drives sustained, physiological IGF-1 production

Recent research suggests they may also benefit brain health and reduce the risk of Alzheimers disease

The most common offenders are hypothyroidism, insulin resistance, PCOS, and elevated cortisol from chronic stress or Cushings syndrome