According to the NIH Office of Dietary Supplements, functional B12 deficiency is most commonly seen in patients with one or more of the following: Age over 50 stomach acid production declines with age, and stomach acid is required to free B12 from food PPI or H2 blocker use reflux medications suppress the acid needed for B12 absorption Metformin use, which interferes with B12 absorption directly Vegan or vegetarian diets B12 is found almost exclusively in animal products Gut conditions including celiac, IBS, SIBO, and Crohns MTHFR mutations that affect how B12 is metabolized once absorbed Heavy alcohol use The symptoms of low B12 are easy to dismiss: fatigue, brain fog, low mood, tingling in the hands or feet, weakness, and shortness of breath on mild exertion
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Vitamin B 12 deficiency Vitamin B 12 deficiency , also known as cobalamin deficiency , is the medical condition in which the blood and tissues have a lower than normal level of vitamin B 12
However you may need to support your vitamin b12 intake and thats when a b12 shot can help you If serum B12 low resume 3 monthly B12 replacement If serum B12 normal , monitor blood count and B12 annually B12 injections work quickly and typically show noticeable effects within 48 to 72 hours
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