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Muscle mass was measured using the appendicular skeletal muscle mass index (ASMI), while muscle function was evaluated through grip strength and gait speed measurements

LC is not restricted to hospitalized patients and its estimated incidence is reported to lie between 10% and 60%, which depends on the definition of LC used and patient cohorts under study (9)

In contrast, cAMP signaling in response to GLP-1 was comparable between wild-type and mutant receptors, supporting the hypothesis that altered signaling with PF-06882961 was not due to a marked alteration of surface expression for the mutated constructs (Fig

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