Aldactone is an aldosterone antagonist (blocker) that is approved to treat the following: Heart failure High blood pressure Swelling (ascites) due to liver (hepatic) cirrhosis Swelling due to nephrotic syndrome (a rare kidney condition) Primary hyperaldosteronism (a condition in which your adrenal gland produces too much hormone called aldosterone) It is also used off-label to treat polycystic ovary syndrome (PCOS), excessive hair growth in women (hirsutism), and acne in women
10.1038/s41598-019-55524-w 9 ChibaY.YamadaT.TsukitaS.TakahashiK.MunakataY.ShiraiY.et al (2016)
The drugs changing from specialty to non-specialty status include: Transplant medicines (e.g., Cellcept) Hepatitis B treatments (e.g., Epivir HBV) Injectable neurological agents (e.g., Botox) Injectable osteoarthritis agents (e.g., Euflexxa) Injectable anticoagulants (e.g., Lovenox)
Ventura-Cots M, Concepcin M, Arranz JA, et al
Lower-dose protocols and real-world practice reports consistently demonstrate that gradual weight reduction occurs when patients maintain the medication and make modest lifestyle adjustments