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Tirzepatide, sold as Mounjaro and Zepbound, works similarly but also targets another hormone, GIP, which may further enhance weight loss

This helps to minimize the risk of an overdose occurring

NICE and British Society for Haematology guidelines recommend: Initial treatment with hydroxocobalamin (the preferred form in the UK) via intramuscular injection For patients without neurological involvement: 1 mg IM three times a week for 2 weeks For patients with neurological involvement: 1 mg IM on alternate days until no further improvement Maintenance: 1 mg every 3 months for patients without neurological involvement