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In a partial hepatectomy-induced behavior study using male Sprague-Dawley rats, surgical trauma induced an exacerbated spatial learning and memory impairment, while exendin-4 treatment suppressed the activation of nuclear factor kappa-B (NF-B) and IL-1, and thus ameliorated hepatectomy-induced behavioral deficits and inflmmation (63)

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Subtract 500 to 1000 calories from the daily total to promote a safe and gradual weight loss

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