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Cellular dysregulation from continuously elevated MOTS-c might have consequences that take years to manifest

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Safety Considerations and Medical Eligibility Screening Both Ro and Fridays implement safety protocols: contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, diabetic retinopathy, and severe kidney disease

Researchers tracking comprehensive metabolic outcomes should monitor blood pressure, lipid panels, and inflammatory markers alongside weight when evaluating either compound