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Anaphylaxis is extremely rare but constitutes a medical emergency requiring immediate treatment with intramuscular adrenaline

10.1016/j.jaut.2017.04.006 117 RameshS.ArachchigeA

Studies have identified an association between the medications and other eye conditions, including diabetic retinopathy and non-arteritic anterior ischemic optic neuropathy (NAION)

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Flat pigmented macules are more characteristic of the conditions described in the literature reviewed here - Laugier-Hunziker macules (Foster and Murray 2026), pigmentary disorder involvement (Jindal et al