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Patients frequently report eating smaller portions and feeling satisfied faster during the first few days, though this sensation intensifies as the drug accumulates in the body over weeks

These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist with a slightly different mechanism

Like many medications, GLP-1 medications can have side effects

Patients experiencing severe dehydration symptoms (dizziness, decreased urination, confusion) or signs of significant electrolyte disturbance (irregular heartbeat, severe fatigue, numbness or tingling) should seek prompt medical care

Dulaglutide offers weekly dosing like semaglutide but with different pharmacokinetics that some patients tolerate better