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Storage & handling Store the sealed lyophilized powder at -20 C, protected from light and moisture

Long-term changes in gut microbial metabolite trimethylamine N-oxide and coronary heart disease risk

Absolute Contraindications The following groups must not use any GLP-1 receptor agonist, including through Amble: Women with a personal or family history of medullary thyroid carcinoma (MTC) Women with Multiple Endocrine Neoplasia syndrome type 2 (MEN2) Women who are currently pregnant Women who are breastfeeding (data insufficient

This plan may include bupropion, naltrexone, metformin, || and/or topiramate

Persistent or worsening nausea should prompt a medical evaluation rather than a self-increased dose