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Insulin resistance: definition and consequences

10.1038/ejhg.2017.22 Eur

For instance, in a parallel-arm randomized controlled trial, 24-h dietary recall was used, and in the group receiving 14 weeks of CR combined with dietary counseling, the percentage of calories from dietary protein increased significantly compared with liraglutide monotherapy, whereas changes in total energy intake were similar between groups [110]

doi: 10.1111/rda.13670 522 MustofaYYulianiFSPurwonoSSadewaAHDamayantiEHeriyantoDS

The practical result is that IGF-1 LR3 requires once-daily dosing and circulates freely in plasma longer, producing sustained receptor activation whereas native IGF-1 would require continuous infusion to maintain therapeutic levels