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Giving a Durolane injection demands careful steps, including using ultrasound or fluoroscopic guidance for accuracy

What is the risk (medications, sensitive digestion, chronic disease)

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They indicated that at a minimum, they would be stopping the trial if they realized a risk reduction of 20% in the treatment arm

In a small, exploratory, randomized, placebo-controlled trial that included 27 cancer patients being treated with a chemotherapy agent known to cause ototoxicity, those given oral D-methionine (100 mg per kg of bodyweight) along with chemotherapy were protected from drug-induced hearing loss