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In a randomized double-blind placebo controlled parallel group comparison trial, the continuous intake of lutein (12 mg) for 16 weeks as a formulation, considering its bio-accessibility, increased macular pigment optical density (MPOD), improved contrast sensitivity, and prevented decreases in visual function caused by a glare from light (Table 1) [80, 81, 8386]

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Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo