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Upon membrane binding, the Syn N-terminal region undergoes a disorder-to-order transition and adopts an -helical conformation, while the acidic C-terminal tail remains disordered 79,80

TB-500 is the closest alternative - arguably more effective for muscle and tendon injuries

doi: 10.1111/j.1365-2362.2004.01381.x

Interest broadened sharply after Yang and colleagues (Cell, 2014) used targeted metabolomic profiling across twelve ferroptosis-inducing small molecules and found that glutathione depletion converges on inactivation of the selenoenzyme glutathione peroxidase 4, placing glutathione availability directly upstream of iron-dependent lipid peroxidation

Cooking methods like air-frying or baking are preferable