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Expectation of immediate, permanent, final results after one session 2030% of patients need a second session to reach optimal volume

The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity

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The disruption extends beyond direct receptor binding-EED exposure significantly impairs recruitment of critical coactivators such as steroid receptor coactivator-1 (SRC-1), substantially weakening AR transcriptional capacity (35)