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In clinical trials: Nearly 24% of people on Wegovy experienced constipation 3%5% of people on Ozempic experienced constipation 5%6% of people on Rybelsus experienced constipation Here are some tips to ease discomfort associated with constipation and get things, ahem, flowing smoothly while your body gets used to the medication

GLP-1 receptor agonist drugs (Ozempic, Victoza, etc.) mimic this natural hormone at its receptor, lasting hours to days instead of 12 minutes

The administration of GLP-1RA or exendin-4 to rats fed a high-fat diet resulted in an increase in the OPG/RANKL ratio and a reduction in the degree of bone loss

They show that its not a willpower issue, that theres underlying biology here

Endocrine Facts and Figures First Edition