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Genuine purging, in the sense of accelerated cell turnover bringing congestion to the surface faster, is mostly discussed with exfoliating actives, not needling, so a breakout in the days after a microneedling session is more often a hygiene issue, bacteria introduced through closing channels by unwashed hands, an unsanitized device, gym sweat, or makeup applied too soon, or a reaction to actives reintroduced too early

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Insufficient amounts of the bait protein may lead to weak or undetectable interactions