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Extracellular matrix studies: Examination of collagen-associated processes

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Laboratory investigations involving aquatic organisms and mammalian models have demonstrated that exposure to certain pharmaceuticals may induce oxidative stress, endocrine disruption, and developmental abnormalities [101, 110]

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This carbonylation impairs mitochondrial respiration, increases superoxide production, and disrupts insulin signaling pathways, contributing to metabolic dysregulation and the progression of metabolic syndrome (84)

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