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Studies have shown that when NNMTi is combined with a lowcalorie diet, the rate of body weight loss in obese mice is significantly faster than in either singleintervention group, with more pronounced reduction of adipose tissue and greater improvement in insulin sensitivity and hepatic metabolism

The data from studies with over 2,000 subjects has shown weight loss reaching 15 to 20 percent of total body weight

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doi: 10.3945/ajcn.116.144931 20

doi: 10.1016/j.jsbmb.2008.06.010