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A randomized, placebo-controlled, phase 1/2 study of tivantinib (ARQ 197) in combination with irinotecan and cetuximab in patients with metastatic colorectal cancer with wild-type KRAS who have received first-line systemic therapy

Furthermore, due to the high prevalence of MASH in the general population, implementing a large-scale evaluation plan using liver biopsy is neither feasible nor advised in current clinical practice [35]

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mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

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