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10.1016/j.redox.2015.09.005 32 DebloisG.St-PierreJ.GigureV

as a result, this mutation incites the MTHFR enzyme to function abnormally or become deactivated

(4) Dose titration: Therapy is typically initiated at low doses and titrated gradually to achieve optimal symptom control while minimizing adverse effects, with the goal of identifying the lowest effective daily dose